Karin Realbrush Pigment markers contain 2.4 ml of opaque acrylic, non-toxic organic pigment-based paint. The filament Realbrush tip is made in Japan. The Realbrush tip requires zero pumping for paint flow - just shake to create! The opaque acrylic paint is beautiful and bright on various colors of paper, plus card stock, glass, most plastics, wood, stone, canvas, and more. It easily blends color-to-color with tonal transitions. It is lightfast and permanent.